What Is Domperidone?
Domperidone is a medication used to treat symptoms of nausea and vomiting associated with various conditions, including gastrointestinal disorders and medication-induced nausea. It is also prescribed for patients with delayed stomach emptying or gastrointestinal reflux disease (GERD). Domperidone works by blocking dopamine receptors in the gut, which helps increase the movement of food and waste through the digestive system.
This medication is commonly used for patients with chronic nausea, bloating, or indigestion that does not respond to conventional treatments. It may also be used in conjunction with other medications to help manage conditions like gastroparesis and improve overall digestive motility.
How Does Domperidone Work?
Domperidone is a dopamine antagonist that works primarily by blocking dopamine receptors in the gastrointestinal tract. By doing so, it promotes gastric motility and speeds up the emptying of the stomach. This helps relieve nausea, bloating, and the discomfort associated with delayed gastric emptying.
Domperidone also has an antiemetic effect, meaning it helps prevent nausea and vomiting, particularly those related to gastrointestinal issues. Unlike some other anti-nausea medications, Domperidone has limited effects on the central nervous system, making it a preferred option for patients who need relief without strong sedative side effects.
Benefits of Using Domperidone
- Helps alleviate nausea and vomiting from various causes
- Improves gastric motility, relieving bloating and indigestion
- Can be used for gastroparesis and other motility disorders
- Reduces symptoms of GERD (gastroesophageal reflux disease)
- Well-tolerated with fewer sedative effects than other antiemetics
- Available in convenient tablet and oral suspension forms
Uses of Domperidone
Domperidone is typically used for:
- Treatment of nausea and vomiting due to gastrointestinal causes or medications
- Managing symptoms of gastroparesis (delayed stomach emptying)
- Helping with GERD and other digestive disorders involving slow gastric motility
- Alleviating bloating and fullness after eating
It is not approved for use in treating conditions other than those listed above and should only be used as prescribed by a healthcare provider.
How to Use Domperidone
Domperidone is usually taken orally in tablet form, typically three times a day, 15 to 30 minutes before meals. For those who have difficulty swallowing tablets, an oral suspension may be available. It’s important to take Domperidone exactly as prescribed by your healthcare provider, and it should be swallowed whole (not chewed).
Never exceed the recommended dosage or duration of use. If you forget to take a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at once to make up for a missed dose.
Domperidone Dosage
The typical starting dose of Domperidone is 10 mg taken three times a day, 15 to 30 minutes before meals. If necessary, your doctor may adjust your dose based on your condition and response to treatment. The maximum recommended dose is 30 mg per day.
Always follow your doctor’s instructions carefully, and never adjust your dosage without consulting them first.
Domperidone Side Effects
Common side effects of Domperidone may include:
- Dry mouth
- Abdominal cramps or bloating
- Diarrhea
- Headache
- Dizziness or lightheadedness
More serious side effects, though rare, can include:
- Heart-related issues, including QT interval prolongation
- Movement disorders such as tremors or stiffness
- Allergic reactions, including rash, itching, or swelling of the face or throat
If you experience any unusual side effects or symptoms, contact your healthcare provider immediately.
Domperidone Overdose
In case of an overdose, seek immediate medical attention or call a poison control center. Symptoms of overdose may include:
- Severe dizziness
- Loss of coordination
- Rapid or irregular heartbeat
- Seizures
Supportive treatment and medical supervision will be necessary for managing an overdose of Domperidone.
Domperidone Missed Dose
If you miss a dose of Domperidone, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take extra medication to make up for a missed dose.
Consistency is important for the effectiveness of this medication, so try to take it at the same time each day.
Warnings and Precautions
Before using Domperidone, inform your healthcare provider if you:
- Have a history of heart conditions, particularly arrhythmias or QT prolongation
- Are pregnant or planning to become pregnant, or are breastfeeding
- Have a history of liver or kidney problems
- Are currently taking other medications, especially those affecting heart rhythm
Domperidone can have serious cardiac side effects, especially in patients with underlying heart conditions. Regular monitoring may be necessary, and the drug should be used cautiously in elderly patients. Domperidone is not recommended for long-term use, and its safety should be periodically reassessed.
Where to Buy Domperidone
Domperidone can be purchased online from Honeybee Pharmacy, a trusted pharmacy partner. Purchasing from a reputable source ensures you are receiving genuine, affordable medication. Ensure you follow your healthcare provider’s guidance when ordering and using Domperidone.
For personalized assistance, you can call our toll-free number to speak with a licensed pharmacist who will be happy to answer your questions and help guide you through the medication process.
Contact Information
If you have any questions about your medication order or need assistance, feel free to call or text us at 1-888-483-1267 (Toll-Free). You can also fax us at 1-888-338-6690. Our support team is available Monday through Friday from 10:00 AM to 8:00 PM CST and on weekends from 9:00 AM to 5:00 PM CST, ensuring help is available every day of the year.
For prompt service, we recommend reaching out to our customer support team during business hours. This allows you to speak directly with a representative for immediate assistance regarding orders, shipping, or product details.
Medication orders from Canada typically arrive within 10-14 business days from the shipping date. Internationally sourced medications may take 15-20 business days to arrive. If you have any concerns about tracking or receiving your order, please call or text 1-888-483-1267 to speak with a member of our loyalty team.
FAQs
Domperidone typically starts working within 30 minutes to an hour after ingestion.
Yes, it can be taken with or without food, but it’s usually more effective when taken before meals.





