What Is Edoxaban?
Edoxaban is an oral anticoagulant medication used to reduce the risk of stroke and blood clots in patients with nonvalvular atrial fibrillation. It is also prescribed for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). Edoxaban belongs to a class of drugs known as direct factor Xa inhibitors, which work by preventing the formation of blood clots through selective inhibition of factor Xa, a key enzyme in the clotting process.
This medication offers the benefit of a predictable anticoagulant effect without the need for frequent blood monitoring, making it a convenient option for many patients requiring long-term anticoagulation therapy.
How Does Edoxaban Work?
Edoxaban selectively blocks factor Xa, an essential enzyme involved in the blood coagulation cascade. By inhibiting factor Xa, Edoxaban interrupts the pathway that leads to blood clot formation. This targeted mechanism helps prevent both the development of new clots and the growth of existing clots.
Unlike older anticoagulants, Edoxaban provides consistent anticoagulation with fewer dietary restrictions and drug interactions, offering greater convenience for patients managing conditions like atrial fibrillation or venous thromboembolism.
Benefits of Using Edoxaban
- Reduces the risk of stroke and systemic embolism in nonvalvular atrial fibrillation
- Treats and prevents deep vein thrombosis (DVT) and pulmonary embolism (PE)
- Convenient once-daily oral dosing
- No routine coagulation monitoring required
- Fewer drug and food interactions compared to traditional anticoagulants
- Rapid onset of action for quicker protection
Uses of Edoxaban
Edoxaban is prescribed for:
- Prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
- Treatment of deep vein thrombosis (DVT)
- Treatment of pulmonary embolism (PE)
- Prevention of recurrence of DVT and PE after initial therapy
Always follow your healthcare provider’s instructions carefully when taking Edoxaban to ensure maximum effectiveness and safety.
Edoxaban Dosage
The typical dosage of Edoxaban depends on the condition being treated, the patient’s kidney function, and other risk factors. Common dosing guidelines include:
- Nonvalvular Atrial Fibrillation: 60 mg once daily
- Treatment of DVT and PE: 60 mg once daily after 5 to 10 days of initial therapy with a parenteral anticoagulant (such as heparin)
A reduced dose of 30 mg once daily may be recommended for patients with impaired kidney function, low body weight (≤60 kg), or those taking certain medications that increase Edoxaban levels.
Edoxaban Side Effects
Common side effects include:
- Easy bruising
- Nosebleeds
- Minor bleeding from gums
Serious side effects requiring immediate medical attention:
- Severe bleeding (uncontrolled bleeding from cuts, blood in urine or stool, coughing up blood)
- Severe headache, dizziness, or fainting
- Signs of allergic reaction (rash, itching, swelling, difficulty breathing)
Patients should contact their healthcare provider immediately if they experience any signs of serious bleeding or unusual symptoms.
Edoxaban Overdose
Taking too much Edoxaban can significantly increase the risk of bleeding complications. Symptoms of overdose may include unusual bruising, bleeding that does not stop, or signs of internal bleeding such as dark urine or black, tarry stools.
If an overdose is suspected, seek emergency medical assistance immediately. Treatment may involve supportive care and, in some cases, administration of reversal agents or blood products.
Edoxaban Missed Dose
If you miss a dose of Edoxaban, take it as soon as you remember on the same day. Do not take two doses at the same time to make up for the missed dose. Simply resume your normal dosing schedule the following day.
Missing doses may increase the risk of clot formation, so try to take Edoxaban at the same time every day.
Warnings and Precautions
Before starting Edoxaban, inform your healthcare provider if you:
- Have kidney disease, liver disease, or bleeding disorders
- Are undergoing surgery, spinal puncture, or have an epidural catheter placed
- Have a history of stroke, especially hemorrhagic stroke
- Are pregnant, planning pregnancy, or breastfeeding
- Are taking other medications that affect blood clotting, such as aspirin, NSAIDs, or other anticoagulants
Edoxaban can increase the risk of serious bleeding, particularly in patients undergoing invasive procedures or with certain underlying health conditions. Careful assessment and planning are required before initiating treatment.
Where to Buy Edoxaban
You can buy Edoxaban online from Honeybee Pharmacy, a trusted pharmacy partner dedicated to providing safe, affordable, and reliable anticoagulant medications. Ordering through a reputable source ensures that you receive genuine Edoxaban, offering peace of mind and protection for your health.
For personalized assistance or help with your prescription, call our toll-free number to speak with a licensed pharmacist from our contracted pharmacy who can guide you through your treatment and answer any questions you may have.
Contact Information
If you have any questions about your medication order or need assistance, feel free to call or text us at 1-888-483-1267 (Toll-Free). You can also fax us at 1-888-338-6690. Our support team is available Monday through Friday from 10:00 AM to 8:00 PM CST and on weekends from 9:00 AM to 5:00 PM CST, ensuring help is available every day of the year.
For prompt service, we recommend reaching out to our customer support team during business hours. This allows you to speak directly with a representative for immediate assistance regarding orders, shipping, or product details.
Medication orders from Canada typically arrive within 10-14 business days from the shipping date. Internationally sourced medications may take 15-20 business days to arrive. If you have any concerns about tracking or receiving your order, please call or text 1-888-483-1267 to speak with a member of our loyalty team.